Selective Maintenance of Multiple CRISPR Arrays Across Prokaryotes

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CRISPR-Cas: the effective immune systems in the prokaryotes

Approximately all sequenced archaeal and half of eubacterial genomes have some sort of adaptive immune system, which enables them to target and cleave invading foreign genetic elements by an RNAi-like pathway. CRISPR–Cas (clustered regularly interspaced short palindromic repeats–CRISPR-associated proteins) systems consist of the CRISPR loci with multiple copies of a short repeat sequence separa...

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Viruses in Prokaryotes CRISPR Provides Acquired Resistance

http://www.sciencemag.org/cgi/content/full/315/5819/1709 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/315/5819/1709/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http:/...

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crispr-cas: the effective immune systems in the prokaryotes

approximately all sequenced archaeal and half of eubacterial genomes have some sort of adaptive immune system, which enables them to target and cleave invading foreign genetic elements by an rnai-like pathway. crispr–cas (clustered regularly interspaced short palindromic repeats–crispr-associated proteins) systems consist of the crispr loci with multiple copies of a short repeat sequence separa...

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Rodolphe Barrangou , Viruses in Prokaryotes CRISPR Provides Acquired

www.sciencemag.org (this information is current as of April 13, 2007 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/315/5819/1709 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/315/5819/1709/DC1 can be foun...

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Small CRISPR RNAs guide antiviral defense in prokaryotes.

Prokaryotes acquire virus resistance by integrating short fragments of viral nucleic acid into clusters of regularly interspaced short palindromic repeats (CRISPRs). Here we show how virus-derived sequences contained in CRISPRs are used by CRISPR-associated (Cas) proteins from the host to mediate an antiviral response that counteracts infection. After transcription of the CRISPR, a complex of C...

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ژورنال

عنوان ژورنال: The CRISPR Journal

سال: 2018

ISSN: 2573-1599,2573-1602

DOI: 10.1089/crispr.2018.0034